Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of this drug either increases the effects of the other by vasodilation which leads to fatal hypotension.
Nitroprusside sodium
The use of this drug is contraindicated because the combination of this drug either increases the effects of the others by pharmacodynamic synergism.
Enzalutamide
Use alternative drugs because the use of enzalutamide will decrease the effect of Sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
Acetazolamide
Therapy should be administered with caution because the use of Sildenafil increases the effect of acetazolamide by pharmacodynamic synergism and it also increases the risk of hypotension.
The use of this medicine can lower blood pressure and when combining it with alcohol further increases the effect. You may experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitation. Also, avoid consuming grapefruit juice because it may increase the effect of avanafil on blood levels.
Cardiovascular disease:
The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with cardiovascular disease. A doctor should consider the vasodilatory effects of this drug and whether they may affect patients with cardiovascular disease. The use of this drug may increase the risk of angina pectoris, AV block, myocardial infarction, ventricular arrhythmia, tachycardia, palpitation, hypotension, postural hypotension, syncope, cerebral thrombosis, cerebrovascular hemorrhage, transient ischemic attack, cardiac arrest, heart failure, and hypertension. These events can occur during or after sexual activity.
Renal dysfunction:
Therapy should be administered with caution in patients with severe renal disease or on renal dialysis. The plasma clearance of this drug is decreased in patients with a severe renal impairment which results in drug accumulation.
Liver diseases:
The use of this drug is not recommended for patients with severe hepatic impairment because the pharmacokinetic disposition of this drug has not been assessed in patients with severe hepatic impairment.
Description: PDE5 is a key enzyme that regulates the process of organ development. It plays a vital role in the maintenance of a proper balance of cyclic guanosine monophosphate (cGMP) in the body. PDE5 inhibitors, such as PDE5i, like other alpha-blockers, may negatively impact the health of patients with erectile dysfunction (ED). This medicine is contraindicated in patients with a known sensitivity to PDE5 inhibitors and in patients with a history of myxedema.The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with erectile dysfunction (ED), as it may increase the effect of sildenafil by inhibiting the metabolism of cGMP. PDE5i can lower the blood pressure and when combined with alcohol, these drugs may cause dizziness, lightheadedness, fainting, headache, and heart palpitation.
Enzalutamide is a membrane-permeable drug that acts as a competitive inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase-5. It may lead to the inhibition of the liver cGMP phosphodiesterase-5, a sensitive reaction that further increases the effect of sildenafil.
The use of this medicine can reduce the amount of fat in the body and may increase the intake of fat-soluble vitamins D, E, and K.
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Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Viagra use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
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Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Viagra use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
asthma are known aswhey- induced asthma?It's possible, but rare, that you may have had an allergic reaction to this drug. Symptoms of an allergic reaction include a rash, itching, swelling, dizziness, trouble breathing.
hiking mitogenated hypokalcca on my way to a business meetingMy brother is diabetic, and he has severe asthma. I asked his doctor if he could get metformin for my blood sugar. He said yes, but he's not getting it from his pharmacy. What I'm not certain is whether or not he has metformin himself, but it's not known if he has metformin himself, either. Is there any connection between metformin and anaphylaxis?
kidney problemsThe FDA says that sildenafil (the active ingredient in Viagra) may rarely cause rare but serious side effects in people with kidney disease. This drug can cause a dangerous drop in blood pressure. It's important to let your doctor know if you have kidney disease before starting this medication.
If you experience any serious side effects, such as severe dizziness, fainting, or rapid heartbeat, seek medical attention immediately. This is a rare side effect which can be fatal if not treated. If your condition does not improve, or gets worse, seek medical attention.
A. W. Fiedorowicz and M. D. Pfeifer..
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